Red Blood Cell (RBC) Morphology (by LabCE)

Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 2 hour(s) Course number 578-022-19, approved through 6/30/2021

Florida Board of Clinical Laboratory Personnel Credit Hours - General (Hematology): 2 hour(s) Course number 20-725570, approved through 9/1/2022

Objectives

• Discuss the procedure for proper red blood cell examination with respect to:
  • objective(s) used
  • area examined
• Discuss various aspects of red cell morphology related to cell size
• Discuss various aspects of red cell morphology related to cell color.
• Discuss various aspects of red cell morphology related to cell shape.

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Course Outline

• Introduction to Red Cell Morphology
• Red Blood Cell (RBC) Morphology
• Assessing RBC Morphology: Area of Evaluation
• Normal RBCs
• Abnormal RBCs
• Artifactual Morphology
• Red Cell Characteristics Related to Size
• MCV and Anisocytosis
• Normal RBC Size
• Microcyte
• Microcyte with Normal Hemoglobin Content
• Macrocyte
• Another Example of Macrocytosis
• Red Cell Characteristics Related to Color
• Hemoglobin Concentration
• Normochromic Red Cells
• Hypochromia and Hyperchromia
• Hypochromia
• Polychromatophilic Red Blood Cells
• Red Cell Characteristics Related to Shape
• Poikilocytosis
• Red Cell Variations in Shape
• Acanthocytes
• Acanthocytes, continued
• Target Cells (Codocytes)
• Target Cells, continued
• Teardrop Cells (Dacrocytes)
• Teardrop Cells, continued
• Sickle Cells (Drepanocytes)
• Sickle Cells, continued
• Burr Cells (Echinocytes)
• Elliptocytes (Ovalocytes)
• Elliptocytes, continued
• Fragmented Red Blood Cells
• Prekeratocytes or Blister Cells
• Keratocytes
• Keratocytes, continued
• Spherocytes
• Conditions Associated with Spherocytes
• Stomatocytes
• Stomatocytes, continued
• Summary
• Red Cell Characteristics Related to Cell Arrangement
• Rouleaux and Autoagglutination
• True Rouleaux
• Artifactual Rouleaux
• Autoagglutination
• Another Example of Autoagglutination
• References
• References

Additional Information

This course describes in detail the morphology of RBCs and their morphological variations in regards to size, shape, and color.

Intended Audience: This course is suitable for clinical laboratory scientists, MT and MLT students, medical students and pathology residents.

Level of Instruction: Basic 

Author Credentials: This course was developed by by Martha MacPherson, R.T. and Marjorie A. Spahn, MT (ASCP), and was updated by Education Materials for Health Professionals, Inc., under the supervision of Marjorie Spahn MT(ASCP). It was adapted for online use by Paul Fekete, MD, FCAP, the President and CEO of MediaLab, Inc. Current review and revision by Barbara Cebulski, MS, MLS(ASCP)
Copyright: Copyright EMHP Inc.,Dayton OH. Licensed to MediaLab Inc., Dacula, GA. Web-based version produced solely by MediaLab Inc.

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