Mathematic Calculations and Applications for the Histology Laboratory (by LabCE)

1.5 P.A.C.E. contact hour(s)

(based on 59 customer ratings)

Carol Becker, MS, MLS(ASCP)CM
Reviewer: Judith M. Thompson, BS, HT(ASCP), HTL

Course provided by LabCE.

See more courses in: Histology

Included In These Course Packages

Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 1.5 hour(s)
Course number 578-068-18, approved through 10/31/2020
Course number 20-684156, approved through 9/1/2020


  • Define terms associated with basic histology math processes.
  • Apply unit conversions within the metric system, including the use of ratio and proportion.
  • Covert temperatures between the Fahrenheit and Celsius systems.
  • Calculate accurate concentrations of solutions, including molar concentrations, normal concentrations, percent concentrations, and conversions between percent and molar solutions.
  • Perform dilution calculations to prepare working solutions from concentrated solutions.
  • Determine the gravimetric factor in staining solution preparation and calculate the amount of dye needed in preparation of new stains.

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(based on 59 customer ratings)

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Course Outline

  • Introduction to Basic Laboratory Math
      • Why do I Need to Understand the Math?
      • Basic Math Applications in the Histology Laboratory
  • The Metric System
      • What is the Metric System?
      • Conversion Within the Metric System
      • Use of Ratio and Proportion
      • Unit Conversion
  • Making Temperature Conversions
      • Conversion Between Fahrenheit and Celsius Scales
  • Calculating Solution Concentrations
      • Defining Solutions
    • Percentage Solutions
      • What is a Percentage Solution?
      • Calculating Percent Weight/Volume (% w/v)
      • Calculating Percent Volume/Volume (% v/v)
      • Calculating Solute Amounts for Percent Solutions
    • Working Solutions
      • Stock Solution Dilutions
    • Molar Solutions
      • What is a Molar Solution?
      • Interchanging Between Percent Concentration and Molarity
    • Normality
      • What is a Normal Solution?
      • Interchanging of Molarity and Normality Concentrations
  • Determining the Gravimetric Factor for Stains
      • What is the Gravimetric Factor?
  • References
      • References

Additional Information

Level of instruction: Basic
Intended audience: This course is appropriate for working histology professionals and for students in histology programs who want a review of basic math applications pertinent to the histology laboratory.
Author information: Carol Becker, MS, MLS(ASCP)CM is a retired Program Director for the Clinical Laboratory Science program and Histology program at OSF St. Francis Medical Center located in Peoria, Illinois. Carol received her Master's degree at the University of St. Francis in Joliet, Illinois and her Bachelor's degree in Medical Laboratory Science from the University of Illinois. 
Reviewer information: Judith Thompson, BS, HTL(ASCP), is a retired histology department manager from OSF Saint Francis Medical Center located in Peoria, Illinois. She also served as Education Coordinator for the OSF St. Francis Histology program. Previous positions include serving as Program Director and Pathology Manager for Christiana Care Hospital/Delaware Community College, Newark, Delaware and Program Director/Pathology Manager/Assistant Director for Takeda-Abbott research project at Allegheny University Hospitals, Philadelphia, Pennsylvania.
Course description: While many changes have occurred in recent years, increased automation in the modern histology laboratory has not diminished the need for mathematical calculations and applications. Immunohistochemical (IHC) staining has become a more routine aspect of the histology workload and challenges personnel to understand and troubleshoot the variables inherent in the preparation and staining process. This course is intended to provide a review of the basic math applications frequently used in the histology laboratory, to provide an opportunity to practice pertinent calculations in preparation for the national certification examination and/or as a refresher for continuing education purposes.

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Histology CE (by LabCE)
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Course provided by LabCE.
Balance scale and graduated cylinder

Celcius to fahrenheit shutterstock

Erlenmeyer flasks shutterstock

Volume to volume solutions

Weight to volume solutions

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