Red Cell Crossmatch Techniques (by LabCE)

2.5 P.A.C.E. contact hour(s)

(based on 718 customer ratings)

Author: Suzanne Butch, MA, MLS(ASCP)CM, SBBCM, DLMCM, CQA(ASQ)
Reviewer: Sheri Goertzen, MT(ASCP)BB, CLS(CA), CQA(ASQ) and Rory Huschka, M.Ed., MT(ASCP)

Course provided by LabCE.

This course covers the various requirements for crossmatching units of packed red cells: patient history, current antibody screen results, and more. Various blood group system antibodies and whether those antibodies are clinically significant is assessed. Different methodologies for carrying out the crossmatch and their associated requirements are also discussed.

See more courses in: Blood Banking / Immunohematology

Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 2.5 hour(s)
Course number 578-123-20, approved through 12/31/2022
Florida Board of Clinical Laboratory Personnel Credit Hours - General (Blood Banking / Immunohematology): 2.5 hour(s)
Course number 20-807032, approved through 9/1/2022

Objectives

  • Describe the various red cell crossmatch methods and their uses
  • Define the common regulations and guidelines for crossmatching of red cells
  • Define requirements for the computer crossmatch
  • Identify the regulations for crosssmatching of red cells
  • Identify accrediting agency requirements for crossmatching of red cells
  • Select the appropriate crossmatch for the scenario described

Customer Ratings

(based on 718 customer ratings)

Course Outline

  • Describe the Various Red Cell Crossmatch Methods and Their Uses
      • Red Cell Crossmatch Techniques
      • Course Objectives
      • Describing Various Crossmatch Techniques
      • What is a Crossmatch?
      • Goals of Method Selection
      • Significant and Insignificant Antibodies
      • Considerations in Method Selection
      • Variables in Methods
      • How Many Readings
      • Antiglobulin Reagents
      • Standard Crossmatch Methods
      • Crossmatch Methods
      • Crossmatch Methods, Continued
      • Antigen Matching
      • Special Crossmatch Methods
      • Special (Rare) Situations
      • Regulatory Requirements for Crossmatching
      • General Requirements
  • Define the common regulations and guidelines for crossmatching of red cells
      • Crossmatch Requirements
      • Crossmatch Requirements, Continued
      • Crossmatch Requirements, Continued
  • Define requirements for the computer crossmatch
      • Computer Crossmatch Requirements
      • Computer Crossmatch Requirements, Continued
      • Computer Crossmatch Requirements, Continued
  • Identify the Regulations for Crossmatching of Red Cells
      • Identify the Regulations for Crossmatching Red Cells
      • Compatibility Testing CFR
      • Compatibility Testing CFR, Continued
      • Compatibility Testing CFR, CLIA
      • Compatibility Testing CFR, FDA
      • Compatibility Testing CFR, Sample Retention
      • CFR, Record Retention
      • CFR, Record Retention, Continued
      • CFR, Record Retention, Continued
      • FDA Guidance on the Electronic Crossmatch
      • More FDA Guidance on the Electronic Crossmatch
      • Donor Unit Requirements
      • Validation
      • Validation, Continued
      • Decision Rule Validation
      • Decision Rules, Warnings
  • Identify Accrediting Agency Requirements for Crossmatching of Red Cells
      • AABB Requirements
      • AABB Requirements, Pretransfusion Testing
      • AABB Requirements, ABO
      • AABB Requirements, Rh
      • AABB Requirements, Continued
      • Serologic Crossmatch
      • Serologic Crossmatch, ABO Incompatibility
      • Unexpected Antibodies
      • Unexpected Antibodies, Continued
      • Computer Use for Detecting ABO Incompatibility
      • Computer Use for Detecting ABO Incompatibility, Continued
      • CAP Requirements for Crossmatching
      • CAP Requirements for Crossmatching, Laboratory Information System Validation
      • CAP Requirements, Age of Specimen
      • CAP Requirements for Crossmatching, Continued
      • CAP Requirements for Crossmatching, Continued
      • CAP Requirements for Crossmatching, Autologous Units
      • CAP Requirements for Crossmatching, Computer Crossmatch
      • CAP Requirements for Crossmatching, ABO and Rh
      • CAP Requirements, Data Entry Verification
      • CAP Requirements, Donor Unit and Recipient Information
      • Joint Commission (TJC) Requirements
      • TJC Requirements, Continued
      • TJC Requirements, Continued
      • TJC Requirements, Continued
      • TJC Requirements, Continued
      • TJC Requirements, Patient Identification and Specimen Labeling
      • TJC Requirements, Specimen Collection and Labeling
      • TJC Requirements, ABO and Rh Typing
      • TJC Requirements, Continued
      • TJC Requirements, Rh Negative
      • TJC Requirements, Written Procedures/Policies
      • TJC Requirements, Continued
      • TJC Requirements, Continued
      • TJC Requirements, Continued
      • TJC Requirements, Continued
      • TJC Requirements, Continued
      • Commission on Office Laboratory Accreditation (COLA) Requirements
      • COLA Requirements, Continued
      • COLA Requirements, Continued
      • COLA Requirements, Continued
      • COLA Requirements, Continued
      • COLA Requirements, Continued
      • COLA Requirements, Continued
  • Select An Appropriate Crossmatch for the Scenarios Described
      • Crossmatching Scenarios
      • Scenario #1
      • Scenario #1, Continued
      • Scenario #2
      • Scenario #2, Continued
      • Scenario #3
      • Scenario #3, Continued
      • Scenario #4
      • Scenario #4, Continued
  • References
      • References

Additional Information

Level of Instruction: Intermediate
Intended Audience: Medical laboratory scientists, medical technologists, and technicians. This course is also appropriate for medical laboratory science students and pathology residents.
Author Information: Suzanne H. Butch, MA, MLS(ASCP)<sup>CM</sup>, SBB, DLM is the Administrative Manager for Healthcare, Blood Bank & Transfusion Service at the University of Michigan Hospitals and Health Centers in Ann Arbor, Michigan. She holds a Bachelors in Medical Technology from the University of Michigan, a Masters Degree in Management and Supervision from Central Michigan University, and Certifications as a Specialist in Blood Bank, as a Quality Audit and as a Diplomate in Laboratory Medicine. She has edited books and written numerous book chapters and articles and has been invited to present numerous lectures in the field of computerization in the blood bank, automation and transfusion medicine.
Reviewer Information: Sheri Goertzen, MT(ASCP)BB, CLS(CA), CQA(ASQ), has over 25 years of experience as the Supervisor of Transfusion Services at Valley Children's Healthcare in Madera, CA. She has almost 40 years of experience in transfusion services. She has been a presenter at AABB conferences and has served on several AABB committees as a contributing member or the committee chair.
Rory Huschka, M.Ed., MT(ASCP), has over 20 years of combined experience as a medical technologist, technical supervisor, professor, and manager. He is the former Director of Medical Laboratory Science and Medical Laboratory Technician Programs at Brookline College. He is currently a Program Director at MediaLab, Inc. Rory holds a BS degree in Medical Technology from North Dakota State University and a Masters in Educational Leadership.  Rory also holds a certificate in Lean/Six Sigma from Villanova University.

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Course provided by LabCE.
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