Red Cell Disorders: Peripheral Blood Clues to Nonneoplastic Conditions (by LabCE)

2 P.A.C.E. contact hour(s)

(based on 463 customer ratings)

Authors: C. William Reiquam, MD; Elmer W. Koneman, MD
Reviewer: Barbara Cebulski, MS, MLS(ASCP)

Course provided by LabCE.

This collection of informative case studies covers many current topics in red cell disorders. Topics include macrocytosis, intracellular RBC inclusions, echinocytes and acanthocytes, schistocytes, ovalocytes, and rouleaux. Numerous high-quality photomicrographs and real-life situations help ensure learning and retaining needed information.

See more courses in: Hematology

Included In These Course Packages

Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 2 hour(s)
Course number 578-060-20, approved through 7/31/2022
Course number 20-784540, approved through 9/1/2022

Objectives

  • Review normal and abnormal red blood cell morphologies.
  • Recall the criteria for performing and reporting peripheral blood smear reviews.
  • Demonstrate ability to evaluate red blood cell size, shape, and staining characteristics.
  • Correlate observations of key red blood cell abnormalities on peripheral smears with associated clinical conditions.
  • Recognize, via case studies, peripheral smear evaluations for red blood cell morphology and their clinical implications.

Customer Ratings

(based on 463 customer ratings)

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Course Outline

  • Introduction to Red Blood Cell Morphology
    • Normal Red Blood Cell Morphology
      • Normal Red Blood Cell (RBC) Characteristics
      • Initial Evaluation of RBC Morphology From Automated Analyzers
      • Criteria for Peripheral Blood Smear Review
    • The Peripheral Smear: Reviewing Red Blood Cell Morphology
      • Introduction to Red Blood Cell Morphology Reporting
      • Guidelines for Reporting Red Blood Cell Morphology
  • Abnormal Red Blood Cell Morphology Review
      • Red Cell Morphology Reference Tables
    • Size Variations in Red Blood Cells
      • Anisocytosis Reference Table
    • Variations in Hemoglobin Content
      • Hemoglobin Content Reference Table
    • Shape Variations in Red Blood Cells
      • Poikilocytosis Review Table
    • Abnormal Red Blood Cell Distribution
      • Rouleaux and Agglutination
      • Dimorphic (Double Cell) Population
    • Red Blood Cell Inclusions
      • Red Blood Cell Inclusions and Associated Conditions
  • Case Studies in Red Blood Cell Nonneoplastic Conditions
      • Introduction to Red Blood Cell Nonneoplastic Conditions Case Studies
    • Hemolytic Conditions with Spherocytosis
      • Macrocytosis-Associated Conditions
        • Intracellular RBC Inclusions
          • Dimorphic Red Blood Cell Populations
            • Target cells and Sickle Cells
              • Hemoglobin E (HbE) and HbE/Beta Thalassemia
            • Schistocytes, Bite Cells, and Teardrop Cells
              • Ovalocytes, Elliptocytes and Stomatocytes
                • Ovalocytes/Elliptocytes
                • Stomatocytes
              • Multiple Erythrocyte Abnormalities
                • Case Study
                • Case Study, continued: Splenectomy Morphologies
                • Case Study, continued: Poikylocytosis and Basophilic Stippling
            • References
                • References

            Additional Information

            Level of Instruction: Intermediate

            Intended Audience: Clinical laboratory science students, and medical technologists and technicians seeking review, cross training, or continuing education opportunities. It is also appropriate for medical students and pathology residents.
             
            Author information: C. William Reiquam, MD (1923-2015) was a clinical professor of pathology in the School of Medicine, University of Colorado. One of his areas of expertise was hematology.

            Author information: Elmer W.Koneman M.D. is Professor Emeritus, Department of Pathology, University of Colorado School of Medicine. Dr. Koneman is a Board Certified Pathologist, former full Professor of Pathology University of Colorado School of Medicine. He is author of numerous journal articles and books.

            Reviewer information: Barbara Cebulski, MS, MLS(ASCP) has over 40 years of experience in the medical laboratory profession as a technologist, hematology section supervisor, and laboratory manager. She was an Inspection and Technical Specialist for nine years with the College of American Pathologists in the Laboratory Accreditation Program and, until her retirement in 2015, was Program Director for MediaLab, Inc. Barbara holds a Masters in Instructional Technology from Georgia State University. 

            Keywords

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            table acantocyte


            table agglutination


            table burr cells


            table macrocytes


            table microcytes


            table target cells


            table sickle cells


            table spherocytes



             
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